failed trials

Graphic showing arrows missing the bullseye on a target

Biotech

How 'overenthusiasm' led to Big Pharma's risky $6B TIGIT gamble

Once hailed as the future of immuno-oncology, it’s been a tough few months for any remaining fans of anti-TIGIT antibodies.

James Waldron Jun 13, 2025 8:00am

three spotlights on a stage

Merck KGaA sheds light on failed portion of phase 2 lupus trial

Jun 12, 2025 9:41am

spotlight purple blue light

Corcept unveils promising survival data from phase 2 ALS fail

Jun 5, 2025 8:21am

Cartoon of businessmen standing around a broken target

Vigil's rare brain disease drug flunks phase 2 study

Jun 4, 2025 9:45am

incomplete railroad tracks in namibia

Sanofi's IL-33 drug fails COPD study

May 30, 2025 5:30am

plan B fail reroute road path trail miss

PepGen ends all DMD work after phase 2 trial falls flat

May 28, 2025 5:30pm